Chemotherapy involves the use of cytotoxic drugs
to kill rapidly dividing cancer cells throughout the body. It is a
systemic treatment, meaning it affects both cancerous and some
normal cells, which can lead to side effects like hair loss, nausea,
and low blood counts. Chemotherapy can be used alone or in
combination with surgery, radiotherapy, or other drugs. Its role
varies by cancer type—it may be given as neoadjuvant (before
surgery or radiation), adjuvant (after local treatment), or palliative
(to control symptoms in advanced cases).
Targeted therapy works by specifically attacking
cancer cells based on their unique genetic or molecular features,
often sparing normal cells. These drugs target specific proteins or
pathways involved in cancer growth, such as HER2 in breast cancer
or EGFR in lung cancer. Unlike chemotherapy, which acts broadly,
targeted therapy is more selective and generally has different (and
sometimes fewer) side effects. It often comes in the form of oral
tablets or IV infusions, and its use depends on specific biomarker
testing of the tumor.
Immunotherapy boosts the body’s own immune
system to recognize and fight cancer cells. It includes various
approaches such as immune checkpoint inhibitors. The checkpoint
inhibitors blocks proteins like PD-1/PD-L1 or CTLA-4 that prevent
immune cells from attacking cancer. Immunotherapy has
revolutionized the treatment of cancers like melanoma, lung
cancer, and kidney cancer, offering durable responses in some
patients. However, it may also trigger immune-related side effects
that need careful monitoring.
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Dr. Abani Kanta Nanda: Best Oncologist In India
Dr. Nanda holds an MBBS and MD in Radiation Oncology from S.C.B. Medical College and Hospital, Cuttack, with advanced training and over five years of post-doctoral experience at the prestigious Acharya Harihar Post Graduate Institute of Cancer (AHPGIC).
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